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Article

Prognostic values of detecting MSI phenotypes in colorectal carcinoma by immunohistochemical method compared to molecular investigation.

La Tunisie medicale - 1 Dec 2017

Trabelsi Mona, Farah Faten, Blel Ahlem, Jaafoura Mohamed Habib, Kharrat Maher, Rammeh Soumaya

Abstract excerpt

BACKGROUND: The identification essentially of hMSH2 and/or hMLH1 alterations has clinical implications for recognition and prognosis of MSI phenotypes cases. In this study, we tried to identify instability by immunohistochemical expression pattern analysis, compared the results with molecular investigation and shown their usefulness as predictive factors for determination of Microsatellite Instability in patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microsatellite Instability

Share to Mismatch Repair Endonuclease PMS2

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Share to MutL Protein Homolog 1

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Source

Identifiers

PMID: 29878286

Genes

PMS2
MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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