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Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth

5 Jun 2018

Abstract excerpt

Cellular senescence (or senescence) has been regarded as a stable form of cell cycle arrest by in vitro cell culture experiments. 1 Recent studies indicate that senescence is associated with aging and diseases, including cancers. 2 , 3 For instances, it suppresses tumor progression by halting the growth of premalignant cells, 4 and promotes wound healing by preventing excessive tissue fibrosis or induction of...

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PMID: 29872106
DOI: 10.1038/s41422-018-0050-6

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