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Article

Alteration of macrophage viability, differentiation, and function by bisphosphonates

5 Jun 2018

Abstract excerpt

BACKGROUND: A serious adverse effect of long-term bisphosphonate (BP) administration is bisphosphonate-related osteonecrosis of the jaw (BRONJ). Among different proposed pathogenesis, suppression of immune cells is gaining interest. Because monocytes/macrophages could get access to BP since residing in the blood and bone microenvironment, the aim of this study was to analyze the behaviors of macrophages after BP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29869362
DOI: 10.1111/odi.12908

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