Article
Macrophages: Their Emerging Roles in Bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2015
Sinder Benjamin P, Pettit Allison R, McCauley Laurie K
Abstract excerpt
Macrophages are present in nearly all tissues and are critical for development, homeostasis, and regeneration. Resident tissue macrophages of bone, termed osteal macrophages, are recently classified myeloid cells that are distinct from osteoclasts. Osteal macrophages are located immediately adjacent to osteoblasts, regulate bone formation, and play diverse roles in skeletal homeostasis. Genetic or pharmacological...
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