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Article

RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy.

Frontiers in immunology - 1 Jan 2018

Chaara Wahiba, Gonzalez-Tort Ariadna, Florez Laura-Maria, Klatzmann David, Mariotti-Ferrandiz Encarnita, Six Adrien

Abstract excerpt

High-throughput sequencing (HTS) has the potential to decipher the diversity of T cell repertoires and their dynamics during immune responses. Applied to T cell subsets such as T effector and T regulatory cells, it should help identify novel biomarkers of diseases. However, given the extreme diversity of TCR repertoires, understanding how the sequencing conditions, including cell numbers, biological and technical...

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Identifiers

PMID: 29868003
DOI: 10.3389/fimmu.2018.01038
PMCID: PMC5962720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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