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Article

The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients.

Frontiers in immunology - 1 Jan 2018

Rohn Hana, Tomoya Michita Rafael, Schwich Esther, Dolff Sebastian, Gäckler Anja, Trilling Mirko, Le-Trilling Vu Thuy Khanh, Wilde Benjamin, Korth Johannes, Heinemann Falko M, Horn Peter A, Kribben Andreas, Witzke Oliver, Rebmann Vera

Abstract excerpt

The interaction of major histocompatibility complex class I chain-related protein A (MICA) and its cognate activating receptor natural killer (NK) group 2 member D (NKG2D) receptor plays a significant role in viral immune control. In the context of kidney transplantation (KTx), cytomegalovirus (CMV) frequently causes severe complications. Hypothesizing that functional polymorphisms of the MICA/NKG2D axis might...

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Share to Cytomegalovirus Infections
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29867932
DOI: 10.3389/fimmu.2018.00917
PMCID: PMC5953334

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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