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Article

Genetic Modifiers of the Breast Tumor Microenvironment.

Trends in cancer - 1 Jun 2018

Flister Michael J, Bergom Carmen

Abstract excerpt

Multiple nonmalignant cell types in the tumor microenvironment (TME) impact breast cancer risk, metastasis, and response to therapy, yet most heritable mechanisms that influence TME cell function and breast cancer outcomes are largely unknown. Breast cancer risk is ∼30% heritable and >170 genetic loci have been associated with breast cancer traits. However, the majority of candidate genes have poorly defined...

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Identifiers

PMID: 29860987
DOI: 10.1016/j.trecan.2018.04.003
PMCID: PMC5990047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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