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Article

Key Pathways and Regulators of Vitamin K Function and Intermediary Metabolism.

Annual review of nutrition - 21 Aug 2018

Shearer Martin J, Okano Toshio

Abstract excerpt

Vitamin K (VK) is an essential cofactor for the post-translational conversion of peptide-bound glutamate to γ-carboxyglutamate. The resultant vitamin K-dependent proteins are known or postulated to possess a variety of biological functions, chiefly in the maintenance of hemostasis. The vitamin K cycle is a cellular pathway that drives γ-carboxylation and recycling of VK via γ-carboxyglutamyl carboxylase (GGCX)...

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Topics

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Share to Gene Expression Regulation, Enzymologic
Share to GGCX gene
Share to Intestinal Absorption

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Vitamin K Epoxide Reductases

Source

Identifiers

PMID: 29856932
DOI: 10.1146/annurev-nutr-082117-051741

Genes

GGCX
UBIAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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