Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Random sorting of Campylobacter jejuni phase variants due to a narrow bottleneck during colonization of broiler chickens.

Microbiology (Reading, England) - 1 Jun 2018

Wanford Joseph J, Lango-Scholey Lea, Nothaft Harald, Hu Yue, Szymanski Christine M, Bayliss Christopher D

Abstract excerpt

Phase variation (PV), involving stochastic switches in gene expression, is exploited by the human pathogen Campylobacter jejuni to adapt to different environmental and host niches. Phase-variable genes of C. jejuni modulate expression of multiple surface determinants, and hence may influence host colonization. Population bottlenecks can rapidly remove the diversity generated by PV, and strict single-cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Vaccines
Share to Biological Variation, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Campylobacter Infections

Share to Campylobacter jejuni

Share to Chickens

Share to Genome, Bacterial

Share to Host-Pathogen Interactions

Share to Poultry Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 29856309
DOI: 10.1099/mic.0.000669
PMCID: PMC6097035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Random sorting of Campylobacter jejuni phase variants due to a narrow bottleneck during colonization of broiler chickens.PMID 29856309Read ↗

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.Semantic proximity Read ↗

Genome-scale dissection of phase-variable gene function in <i>Campylobacter jejuni</i> using a stabilized phasotype librarySemantic proximity Read ↗

Phase variable genes of Campylobacter jejuni exhibit high mutation rates and specific mutational patterns but mutability is not the major determinant of population structure during host colonization.Semantic proximity Read ↗

Phase Variation During Host Colonization and Invasion by Campylobacter jejuni and Other Campylobacter SpeciesSemantic proximity Read ↗

Passage of Campylobacter jejuni through the chicken reservoir or mice promotes phase variation in contingency genes Cj0045 and Cj0170 that strongly associates with colonization and disease in a mouse model.Semantic proximity Read ↗

Phage exposure causes dynamic shifts in the expression states of specific phase-variable genes of Campylobacter jejuni.Semantic proximity Read ↗

Generation and Screening of an Insertion Sequencing-Compatible Mutant Library of Campylobacter jejuni.Semantic proximity Read ↗

Stabilizing Genetically Unstable Simple Sequence Repeats in the Campylobacter jejuni Genome by Multiplex Genome Editing: a Reliable Approach for Delineating Multiple Phase-Variable Genes.Semantic proximity Read ↗

Campylobacter phages use hypermutable polyG tracts to create phenotypic diversity and evade bacterial resistance.Semantic proximity Read ↗

Point mutations in the major outer membrane protein drive hypervirulence of a rapidly expanding clone of <i>Campylobacter jejuni</i>Semantic proximity Read ↗

Genomic tailoring of autogenous poultry vaccines to reduce Campylobacter from farm to forkSemantic proximity Read ↗

Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.