Article
Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation.
PLoS pathogens - 1 Mar 2018
Beare Paul A, Jeffrey Brendan M, Long Carrie M, Martens Craig M, Heinzen Robert A
Abstract excerpt
Coxiella burnetii is an intracellular pathogen that causes human Q fever, a disease that normally presents as a severe flu-like illness. Due to high infectivity and disease severity, the pathogen is considered a risk group 3 organism. Full-length lipopolysaccharide (LPS) is required for full virulence and disease by C. burnetii and is the only virulence factor currently defined by infection of an immunocompetent...
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