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Article

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

mBio - 4 Apr 2017

Aidley Jack, Rajopadhye Shweta, Akinyemi Nwanekka M, Lango-Scholey Lea, Jones Michael A, Bayliss Christopher D

Abstract excerpt

Phase variation occurs in many pathogenic and commensal bacteria and is a major generator of genetic variability. A putative advantage of phase variation is to counter reductions in variability imposed by nonselective bottlenecks during transmission. Genomes of Campylobacter jejuni, a widespread food-borne pathogen, contain multiple phase-variable loci whose rapid, stochastic variation is generated by...

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PMID: 28377533
DOI: 10.1128/mBio.02311-16
PMCID: PMC5380846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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