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Article

A distinct cohort of the TGFβ superfamily members expressed in human endometrium regulate decidualization

23 Apr 2008

Abstract excerpt

BACKGROUND: Successful blastocyst implantation requires the differentiation of human endometrial stromal cells (HESC), a process known as decidualization. Activin A, a transforming growth factor beta (TGFbeta) superfamily member, enhances HESC decidualization and localizes to decidual cells in human endometrium. Other TGFbeta superfamily members, including BMP2, BMP4, BMP7, GDF5, GDF8, GDF11, TGFbetas and Nodal,...

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PMID: 18434375
DOI: 10.1093/humrep/den110

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