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Genetic Variants of CYP2R1 Are Key Regulators of Serum Vitamin D Levels and Incidence of Myocardial Infarction in Middle-Aged Egyptians.

Current pharmaceutical biotechnology - 1 Jan 2018

Sedky Nada K, Abdel Rahman Mohamed F, Hassanein Sally I, Gad Mohamed Z

Abstract excerpt

BACKGROUND: Myocardial Infarction (MI) is one of the leading causes of morbidity and mortality in Egypt and worldwide. Vitamin D deficiency has long been linked to incidence of cardiovascular diseases. Several factors were reported to contribute to serum vitamin D level including exposure to sunlight. However, genetic variations in the vitamin D metabolic pathways have also been considered as strong determinants...

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PMID: 29804528
DOI: 10.2174/1389201019666180528082737

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