Genetic Variations in the Vitamin D Receptor Predict Type 2 Diabetes and Myocardial Infarction in a Community-Based Population: The Tromsø Study.

doi:10.1371/journal.pone.0145359

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Article

Genetic Variations in the Vitamin D Receptor Predict Type 2 Diabetes and Myocardial Infarction in a Community-Based Population: The Tromsø Study.

PloS one - 1 Jan 2015

Zostautiene Ieva, Jorde Rolf, Schirmer Henrik, Mathiesen Ellisiv Bøgeberg, Njølstad Inger, Løchen Maja-Lisa, Wilsgaard Tom, Joakimsen Ragnar Martin, Kamycheva Elena

Abstract excerpt

BACKGROUND: Though the associations between low serum 25-hydroxyvitamin D (25(OH)D) levels and health outcomes such as type 2 diabetes (T2D), myocardial infarction (MI), cancer, and mortality are well-studied, the effect of supplementation with vitamin D is uncertain. This may be related to genetic differences. Thus, rs7968585, a single nucleotide polymorphism (SNP) of the vitamin D receptor (VDR), has recently...

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PMID: 26699871
DOI: 10.1371/journal.pone.0145359
PMCID: PMC4689352

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