Article
Triangular relationship between single nucleotide polymorphisms in the CYP2R1 gene (rs10741657 and rs12794714), 25-hydroxyvitamin d levels, and coronary artery disease incidence.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Sept 2014
Hassanein Sally I, Abu El Maaty Mohamed A, Sleem Hameis M, Gad Mohamed Z
Abstract excerpt
OBJECTIVE: To investigate the relationship between the rs10741657 and rs12794714 polymorphisms in the CYP2R1 gene, 25(OH)D levels, and coronary artery disease (CAD) incidence. METHODS: In total, 134 male patients with verified CAD were recruited, alongside 109 age- and sex-matched controls. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism, using the corresponding...
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