Autophagy impairment in Parkinson's disease.

Abstract excerpt

Parkinson's disease (PD) is a debilitating movement disorder typically associated with the accumulation of intracytoplasmic aggregate prone protein deposits. Over recent years, increasing evidence has led to the suggestion that the mutations underlying certain forms of PD impair autophagy. Autophagy is a degradative pathway that delivers cytoplasmic content to lysosomes for degradation and represents a major...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy
• Share to Autophagy in Disease and Therapy
• Share to Lysosomal Storage Disorders Research