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Article

A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease.

Scientific reports - 24 May 2018

Sun Chiao-Yin, Wu Mai-Szu, Lee Chin-Chan, Chen Shu-Hong, Lo Kang-Chieh, Chen Yau-Hung

Abstract excerpt

We aimed to analyze the associations of single nucleotide polymorphisms (SNP) in the 5' regulatory region of the human organic anion transporter 1 (OAT1) gene with chronic kidney disease (CKD). A case-control study including age- and sex-matched groups of normal subjects and patients with CKD (n = 162 each) was designed. Direct sequencing of the 5' regulatory region (+88 to -1196 region) showed that patients with...

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Identifiers

PMID: 29795395
DOI: 10.1038/s41598-018-26460-y
PMCID: PMC5967335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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