Article
Diagnosis for carcinoma of unknown primary site with the aid of simple PCR tests: a single-center experience.
Neoplasma - 14 Mar 2018
Suspitsin E, Yanus G, Imyanitov E
Abstract excerpt
This study was aimed to incorporate PCR testing in the determination of organ/tissue origin for cancers of unknown primary site (CUP). We developed a PCR panel consisting of 7 expression markers (CDX2, CDH17, SPB, UGRP, MAM, LPB, TG) and 2 genes frequently mutated in cancer (KRAS and BRAF). The expression tests were intentionally interpreted in a non-quantitative way, i.e. classified tumors either as positive or...
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