Article
Monogenic systemic lupus erythematosus: insights in pathophysiology.
Rheumatology international - 1 Oct 2018
Batu Ezgi Deniz
Abstract excerpt
Systemic lupus erythematosus (SLE) is a complex disease with different genetic, immunologic, and environmental factors contributing to the pathogenesis. Monogenic SLE could help us understand the main phases of immune dysregulation in SLE. The aim of this review is to summarize the current knowledge on monogenic SLE with the implications of the respective genes on disease pathogenesis. A comprehensive literature...
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