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Article

Childhood asthma: pathogenesis and phenotypes.

The European respiratory journal - 1 Jun 2022

Pijnenburg Mariëlle W, Frey Urs, De Jongste Johan C, Saglani Sejal

Abstract excerpt

In the pathogenesis of asthma in children there is a pivotal role for a type 2 inflammatory response to early life exposures or events. Interactions between infections, atopy, genetic susceptibility and environmental exposures (such as farmyard environment, air pollution and tobacco smoke exposure) influence the development of wheezing illness and the risk of progression to asthma. The immune system, lung...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34711541
DOI: 10.1183/13993003.00731-2021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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