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Article

Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation.

Blood - 8 Apr 2010

Sood Raman, English Milton A, Belele Christiane L, Jin Hao, Bishop Kevin, Haskins Rebecca, McKinney Mary Cathleen, Chahal Jagman, Weinstein Brant M, Wen Zilong, Liu P Paul

Abstract excerpt

Runx1 is required for the emergence of hematopoietic stem cells (HSCs) from hemogenic endothelium during embryogenesis. However, its role in the generation and maintenance of HSCs during adult hematopoiesis remains uncertain. Here, we present analysis of a zebrafish mutant line carrying a truncat...

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Identifiers

PMID: 20154212
DOI: 10.1182/blood-2009-08-236729
PMCID: PMC2854427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20154212-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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