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Article

Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?

27 Apr 2018

Abstract excerpt

The role of phagocytosis in the neuroprotective function of microglia has been appreciated for a long time, but only more recently a dysregulation of this process has been recognized in Parkinson's disease (PD). Indeed, microglia play several critical roles in central nervous system (CNS), such as clearance of dying neurons and pathogens as well as immunomodulation, and to fulfill these complex tasks they engage...

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PMID: 29755317
DOI: 10.3389/fnmol.2018.00144

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