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Article

Selenate sensitivity of a laeA mutant is restored by overexpression of the bZIP protein MetR in Aspergillus fumigatus.

Fungal genetics and biology : FG & B - 1 Aug 2018

Jain Sachin, Sekonyela Relebohile, Knox Benjamin P, Palmer Jonathan M, Huttenlocher Anna, Kabbage Mehdi, Keller Nancy P

Abstract excerpt

LaeA is a conserved global regulator of secondary metabolism and development in filamentous fungi. Examination of Aspergillus fumigatus transcriptome data of laeA deletion mutants have been fruitful in identifying genes and molecules contributing to the laeA mutant phenotype. One of the genes significantly down regulated in A. fumigatus ΔlaeA is metR, encoding a bZIP DNA binding protein required for sulfur and...

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Identifiers

PMID: 29753128
DOI: 10.1016/j.fgb.2018.05.001
PMCID: PMC6064392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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