Article
Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus.
Fungal genetics and biology : FG & B - 1 Oct 2008
Kale Shubha P, Milde Lane, Trapp Marisa K, Frisvad Jens C, Keller Nancy P, Bok Jin Woo
Abstract excerpt
The nuclear regulator LaeA has been shown to govern production of multiple secondary metabolites in Aspergillus nidulans and Aspergillus fumigatus. Herein we examine the role of this protein in Aspergillus flavus. Similarly as in other Aspergilli, LaeA had a major effect on A. flavus secondary metabolism where DeltalaeA and over-expression laeA (OE::laeA) strains yielded opposite phenotypes resulting in decreased...
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