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Article

Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator.

G3 (Bethesda, Md.) - 1 Feb 2013

Karimi-Aghcheh Razieh, Bok Jin Woo, Phatale Pallavi A, Smith Kristina M, Baker Scott E, Lichius Alexander, Omann Markus, Zeilinger Susanne, Seiboth Bernhard, Rhee Catherine, Keller Nancy P, Freitag Michael, Kubicek Christian P

Abstract excerpt

The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi, and it can modify heterochromatin structure in Aspergillus nidulans. We have recently shown that the LaeA ortholog of Trichoderma reesei (LAE1), a fungus that is an industrial producer of cellulase and hemicellulase enzymes, regulates the expression of cellulases...

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Identifiers

PMID: 23390613
DOI: 10.1534/g3.112.005140
PMCID: PMC3564997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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