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Article

A novel automethylation reaction in the Aspergillus nidulans LaeA protein generates S-methylmethionine.

The Journal of biological chemistry - 17 May 2013

Patananan Alexander N, Palmer Jonathan M, Garvey Graeme S, Keller Nancy P, Clarke Steven G

Abstract excerpt

The filamentous fungi in the genus Aspergillus are opportunistic plant and animal pathogens that can adapt to their environment by producing various secondary metabolites, including lovastatin, penicillin, and aflatoxin. The synthesis of these small molecules is dependent on gene clusters that are globally regulated by the LaeA protein. Null mutants of LaeA in all pathogenic fungi examined to date show decreased...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23532849
DOI: 10.1074/jbc.M113.465765
PMCID: PMC3656261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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