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Article

Malignant primary diffuse leptomeningeal gliomatosis with histone H3.3 K27M mutation.

Neuro-Chirurgie - 1 Jun 2018

Champeaux C, Drier A, Devaux B, Tauziède-Espariat A

Abstract excerpt

INTRODUCTION: Malignant primary diffuse leptomeningeal gliomatosis (MPDLG) are rare central nervous system neoplasms associated with a poor outcome. CASE REPORT: We report the case of a 40-year-old woman who presented with unusual worsening of bilateral sciatica, headaches, diplopia and a left proptosis. MRI of the head and spine showed multiple leptomeningeal lesions with no intra parenchymal involvement. The...

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PMID: 29752148
DOI: 10.1016/j.neuchi.2017.12.007

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