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Article

Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity.

BMC medical genetics - 11 May 2018

Hu Hao, Li Haiyan, Li Jieqiong, Yu Jintai, Tan Lan

Abstract excerpt

BACKGROUND: The activity of cerebrospinal fluid (CSF) β-site APP cleaving enzyme (BACE) is a potential diagnostic biomarker for Alzheimer disease (AD). METHODS: A total of 340 non-Hispanic Caucasian participants from the Alzheimer's Disease Neuroimaging Initiative cohort (ADNI) database were included in this study with quality-controlled CSF BACE and genotype data. Association of CSF BACE with the genetic...

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Source

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Identifiers

PMID: 29751835
DOI: 10.1186/s12881-018-0603-z
PMCID: PMC5948839

Genes

APP
CDH23
RGS20
RORA
SNX31

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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