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Article

Microsatellite Instability Occurs Rarely in Patients with Cholangiocarcinoma: A Retrospective Study from a German Tertiary Care Hospital.

International journal of molecular sciences - 9 May 2018

Winkelmann Ria, Schneider Markus, Hartmann Sylvia, Schnitzbauer Andreas A, Zeuzem Stefan, Peveling-Oberhag Jan, Hansmann Martin Leo, Walter Dirk

Abstract excerpt

Immune-modulating therapy is a promising therapy for patients with cholangiocarcinoma (CCA). Microsatellite instability (MSI) might be a favorable predictor for treatment response, but comprehensive data on the prevalence of MSI in CCA are missing. The aim of the current study was to determine the prevalence of MSI in a German tertiary care hospital. Formalin-fixed paraffin-embedded tissue samples, obtained in...

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Source

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Identifiers

PMID: 29747443
DOI: 10.3390/ijms19051421
PMCID: PMC5983652

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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