Article
[Phenotype and mechanism of inducible ppp2r1a knockout mouse model].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 6 May 2018
Fan J L, Wang F P, Wang S, Liu X L, Wu X N, Chen W, Chen L P, Li W X
Abstract excerpt
Objective: Investigate the effects of inducible ppp2r1a knockout on main physiological function in adult mice and study the mechanism. Methods: Ppp2r1a(flox/flox) mice and CAGG-CreER mice were hybridized to obtain 20 CAGG-CreER ppp2r1a(flox/flox) and 20 mice in homozygous group. Two groups of mice were divided into 4 groups respectively, finally we got 8 groups with 5 mice in each group. Tamoxifen was injected...
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