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Article

Molecular basis of benzimidazole inhibitors to hepatitis C virus envelope glycoprotein.

Chemical biology & drug design - 1 Sept 2018

Uddin Reaz, Downard Kevin M

Abstract excerpt

The molecular basis for the inhibitory action of a benzimidazole inhibitor compound to hepatitis C virus E1 envelope protein was examined computationally. Structures for the wild-type E1 protein and seven mutants were modelled using an ab initio protein structure prediction algorithm, and these models were docked with the benzimidazole inhibitor. Top-ranked conformers for each docked structure were examined in...

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Share to Benzimidazoles
Share to Databases, Protein
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Structure, Tertiary

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Identifiers

PMID: 29745064
DOI: 10.1111/cbdd.13329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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