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[Construction of SPA7074-deficient mutant of biocontrol strain Streptomyces pactum Act12 and characterization of its secondary metabolites].

Wei sheng wu xue bao = Acta microbiologica Sinica - 4 Dec 2016

Duan Xuemei, Zhao Feiyang, Yan Xia, Xue Quanhong, Li Xiaoxia, Wen Bingjie, Jia Lianghui, Yan Hua

Abstract excerpt

Objective: To disrupt spa7074, which encodes a member of the TetR family transcriptional factors, in biocontrol strain Act12 and characterize the secondary metabolites in the mutant strain. Methods: We disrupted the gene spa7074 by homologous recombination. The secondary metabolites of the mutant strain Δspa7074 and Act12 were detected by HPLC. The structure was analyzed by MS and NMR. Results: Compared to the...

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PMID: 29741854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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