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Article

ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages.

Circulation - 16 Oct 2018

Laguna-Fernandez Andres, Checa Antonio, Carracedo Miguel, Artiach Gonzalo, Petri Marcelo H, Baumgartner Roland, Forteza Maria J, Jiang Xintong, Andonova Teodora, Walker Mary E, Dalli Jesmond, Arnardottir Hildur, Gisterå Anton, Thul Silke, Wheelock Craig E, Paulsson-Berne Gabrielle, Ketelhuth Daniel F J, Hansson Göran K, Bäck Magnus

Abstract excerpt

BACKGROUND: In addition to enhanced proinflammatory signaling, impaired resolution of vascular inflammation plays a key role in atherosclerosis. Proresolving lipid mediators formed through the 12/15 lipoxygenase pathways exert protective effects against murine atherosclerosis. n-3 Polyunsaturated fatty acids, including eicosapentaenoic acid (EPA), serve as the substrate for the formation of lipid mediators, which...

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Identifiers

PMID: 29739755
DOI: 10.1161/CIRCULATIONAHA.117.032801
PMCID: PMC6200387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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