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Article

A correlation between capsid protein VP2 and the plaque morphology of African horse sickness virus in cell culture.

Virus genes - 1 Aug 2018

Schade-Weskott Mathilde L, van Schalkwyk Antoinette, Koekemoer J J O

Abstract excerpt

The attenuated live virus vaccine that is used in South Africa to protect against African horse sickness infection was developed more than 50 years ago. With the selection of the vaccine strains by cell culture passage, a correlation between the size of plaques formed in monolayer Vero cultures and attenuation of virus virulence in horses was found. The large plaque phenotype was used as an indication of cell...

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Identifiers

PMID: 29730763
DOI: 10.1007/s11262-018-1567-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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