Article
Membrane association of African horsesickness virus nonstructural protein NS3 determines its cytotoxicity.
Virology - 20 Jan 2001
van Niekerk M, Smit C C, Fick W C, van Staden V, Huismans H
Abstract excerpt
The smallest RNA genome segment of African horsesickness virus (AHSV) encodes the nonstructural protein NS3 (24K). NS3 localizes in areas of plasma membrane disruption and is associated with events of viral release. Conserved features in all AHSV NS3 proteins include the synthesis of a truncated NS3A protein from the same open reading frame as that of NS3, a proline-rich region, a region of strict sequence...
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