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Article

Genomic evolution of Staphylococcus aureus isolates colonizing the nares and progressing to bacteremia

3 May 2018

Abstract excerpt

BACKGROUND: Nasal colonization by Staphylococcus aureus is a key risk factor for bacteremia. The objective of this study is to identify genomic modifications occurring in nasal carriage strains of S. aureus as they progress to bacteremia in a cohort of hospitalized patients. METHODS: Eight patients with S. aureus bacteremia were identified. Genomic sequences of the bloodstream isolates were compared with 57 nasal...

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PMID: 29723202
DOI: 10.1371/journal.pone.0195860

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