Article
Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice.
Frontiers in immunology - 1 Jan 2018
Pan Li-Long, Deng Yuan-Yuan, Wang Ruxing, Wu Chengfei, Li Jiahong, Niu Wenying, Yang Qin, Bhatia Madhav, Gudmundsson Gudmundur H, Agerberth Birgitta, Diana Julien, Sun Jia
Abstract excerpt
Acute pancreatitis (AP) is one common clinical acute abdominal disease, for which specific pharmacological or nutritional therapies remain elusive. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory functions. The current study aimed to investigate potential modulatory effects of lactose and the interplay between the nutrient and pancreatic immunity during...
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