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Article

Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.

Journal of the National Cancer Institute - 1 Dec 2018

Loree Jonathan M, Bailey Ann M, Johnson Amber M, Yu Yao, Wu Wenhui, Bristow Christopher A, Davis Jennifer S, Shaw Kenna R, Broaddus Russell, Banks Kimberly C, Lanman Richard B, Meric-Bernstam Funda, Overman Michael J, Kopetz Scott, Raghav Kanwal

Abstract excerpt

Background: Despite growing therapeutic relevance of ERBB2 amplifications in colorectal cancer (CRC), little is known about ERBB2/ERBB3 mutations. We aimed to characterize these subsets of CRC. Methods: We performed a retrospective analysis of 419 CRC patients from MD Anderson (MDACC) and 619 patients from the Nurses' Health Study (NHS)/Health Professionals Follow-Up Study (HPFS) with tissue sequencing,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29718453
DOI: 10.1093/jnci/djy067
PMCID: PMC6292791

Genes

ERBB2
ERBB3
NHS
APC
BRAF
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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