Article
Linking Pathogenic Mechanisms of Alcoholic Liver Disease With Clinical Phenotypes.
Gastroenterology - 1 Jun 2016
Nagy Laura E, Ding Wen-Xing, Cresci Gail, Saikia Paramananda, Shah Vijay H
Abstract excerpt
Alcoholic liver disease (ALD) develops in approximately 20% of alcoholic patients, with a higher prevalence in females. ALD progression is marked by fatty liver and hepatocyte necrosis, as well as apoptosis, inflammation, regenerating nodules, fibrosis, and cirrhosis.(1) ALD develops via a complex process involving parenchymal and nonparenchymal cells, as well as recruitment of other cell types to the liver in...
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