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Systematic transcriptome analysis reveals elevated expression of alcohol‐metabolizing genes in NAFLD livers

28 Sept 2015

Abstract excerpt

Obese animals and non-alcoholic fatty liver disease (NAFLD) patients exhibit elevated blood alcohol, suggesting potential contributions of alcohol metabolism to the development of NAFLD. Liver gene expression in patients with biopsy-proven mild (N = 40) and severe (N = 32) NAFLD were compared to that in healthy liver donors (N = 7) and alcoholic hepatitis (AH; N = 15) using microarrays. Principal components...

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PMID: 26415102
DOI: 10.1002/path.4650

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