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Article

Associations Between Genomic Variants in lncRNA-TRPM2-AS and lncRNA-HNF1A-AS1 Genes and Risk of Multiple Sclerosis.

Journal of molecular neuroscience : MN - 1 Jul 2020

Bahrami Tayyeb, Taheri Mohammad, Omrani Mir Davood, Karimipoor Morteza

Abstract excerpt

Multiple sclerosis (MS) is a complex genetic trait characterized by demyelination of central nervous system (CNS), inflammation, and progressive neurological dysfunction. There is evidenced that autophagy and stress mechanisms are tightly linked with MS. Previous studies have demonstrated that LncRNAs TRPM2-AS and HNF1A-AS1 are involved in oxidative stress and autophagy, respectively. In the current study, we...

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PMID: 32100228
DOI: 10.1007/s12031-020-01504-z

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