Article
Genetic variants within ANRIL (antisense non coding RNA in the INK4 locus) are associated with risk of psoriasis.
International immunopharmacology - 1 Jan 2020
Rakhshan Azadeh, Zarrinpour Nader, Moradi Afshin, Ahadi Mahsa, Omrani Mir Davood, Ghafouri-Fard Soudeh, Taheri Mohammad
Abstract excerpt
BACKGROUND: Psoriasis is a systemic inflammatory disease which mostly affects skin. Evidences support the role of autoimmune responses in this disorder. The long non-coding RNA (lncRNA) antisense non coding RNA in the INK4 locus (ANRIL) has been shown to participate in modulation of immune response and in the pathogenesis of immune-related disorders. METHODS: We genotyped four single nucleotide polymorphisms...
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