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Clustering of HR + /HER2- breast cancer in an Asian cohort is driven by immune phenotypes.

Breast cancer research : BCR - 22 Apr 2024

Pan Jia-Wern, Ragu Mohana, Chan Wei-Qin, Hasan Siti Norhidayu, Islam Tania, Teoh Li-Ying, Jamaris Suniza, See Mee-Hoong, Yip Cheng-Har, Rajadurai Pathmanathan, Looi Lai-Meng, Taib Nur Aishah Mohd, Rueda Oscar M, Caldas Carlos, Chin Suet-Feung, Lim Joanna, Teo Soo-Hwang

Abstract excerpt

Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian population, by analysing the transcriptomic profiles of 934 breast cancer patients from a Malaysian cohort. Our findings reveal that the HR + /HER2- breast cancer samples display a...

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Identifiers

PMID: 38649964
DOI: 10.1186/s13058-024-01826-5
PMCID: PMC11035138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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