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Article

Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer.

PLoS neglected tropical diseases - 1 Apr 2018

Vincent Quentin B, Belkadi Aziz, Fayard Cindy, Marion Estelle, Adeye Ambroise, Ardant Marie-Françoise, Johnson Christian R, Agossadou Didier, Lorenzo Lazaro, Guergnon Julien, Bole-Feysot Christine, Manry Jeremy, Nitschké Patrick, Theodorou Ioannis, Casanova Jean-Laurent, Marsollier Laurent, Chauty Annick, Abel Laurent, Alcaïs Alexandre

Abstract excerpt

Buruli ulcer (BU), the third most frequent mycobacteriosis worldwide, is a neglected tropical disease caused by Mycobacterium ulcerans. We report the clinical description and extensive genetic analysis of a consanguineous family from Benin comprising two cases of unusually severe non-ulcerative BU. The index case was the most severe of over 2,000 BU cases treated at the Centre de Dépistage et de Traitement de la...

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Identifiers

PMID: 29708969
DOI: 10.1371/journal.pntd.0006429
PMCID: PMC5945055

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