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Article

Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana.

PLoS neglected tropical diseases - 20 Jul 2010

Röltgen Katharina, Qi Weihong, Ruf Marie-Thérèse, Mensah-Quainoo Ernestina, Pidot Sacha J, Seemann Torsten, Stinear Timothy P, Käser Michael, Yeboah-Manu Dorothy, Pluschke Gerd

Abstract excerpt

Buruli ulcer (BU) is an emerging necrotizing disease of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. While proximity to stagnant or slow flowing water bodies is a risk factor for acquiring BU, the epidemiology and mode of M. ulcerans transmission is poorly understood. Here we have used high-throughput DNA sequencing and comparisons of the genomes of seven M. ulcerans isolates that appeared...

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Identifiers

PMID: 20652033
DOI: 10.1371/journal.pntd.0000751
PMCID: PMC2907412

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Source receipt: pubmed, retrieved 7 Sept 2026.

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