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Article

Clonal T cell receptor gene rearrangements in coeliac disease: implications for diagnosing refractory coeliac disease.

Journal of clinical pathology - 1 Sept 2018

Hussein Shafinaz, Gindin Tatyana, Lagana Stephen M, Arguelles-Grande Carolina, Krishnareddy Suneeta, Alobeid Bachir, Lewis Suzanne K, Mansukhani Mahesh M, Green Peter H R, Bhagat Govind

Abstract excerpt

AIMS: Refractory coeliac disease type II (RCDII), a rare complication of coeliac disease (CD) associated with high morbidity, requires identification of a clonal population of phenotypically aberrant intraepithelial lymphocytes (IELs) for diagnosis. However, data regarding the frequency and significance of clonal T cell receptor (TCR) gene rearrangements (TCR-GRs) in small bowel (SB) biopsies of patients without...

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PMID: 29703761
DOI: 10.1136/jclinpath-2018-205023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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