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Article

GALNT14 Involves the Regulation of Multidrug Resistance in Breast Cancer Cells

24 Apr 2018

Abstract excerpt

GALNT14 is a member of N-acetylgalactosaminyltransferase enzyme family and mediates breast cancer cell development. Here, we find that GALNT14 regulates multidrug resistance (MDR) in breast cancer. The expression of GALNT14 is associated with MDR in breast cancer. Higher level of GALNT14 facilitates MCF-7 cells to resist Adriamycin, whereas knockdown of GALNT14 sensitizes cells to Adriamycin. Moreover, the...

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PMID: 29702465
DOI: 10.1016/j.tranon.2018.04.003

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