Article
KRAS fluorescence in situ hybridisation testing for the detection and diagnosis of pancreatic adenocarcinoma.
Journal of clinical pathology - 1 Oct 2018
Shiroma Noriyuki, Arihiro Koji, Oda Miyo, Orita Makoto
Abstract excerpt
AIMS: The aim of our study was to analyse correlations between KRAS mutation status, chromosomal changes that affect KRAS status in cells from pancreatic tumours. METHODS: We collected 69 cases of surgically resected pancreatic ductal adenocarcinoma (PDA) and seven cases of chronic pancreatitis (CP). Chromosomal abnormalities of KRAS and CEP12 were detected using fluorescence in situ hybridisation (FISH)....
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