Article
Serological responses to rotavirus NSP2 following administration of RV3-BB human neonatal rotavirus vaccine.
Human vaccines & immunotherapeutics - 1 Jan 2018
Cowley Daniel, Pavlic Daniel, Bogdanovic-Sakran Nada, Boniface Karen, Kirkwood Carl D, Bines Julie E
Abstract excerpt
Serum rotavirus IgA responses are an imperfect non-mechanistic correlate of protection, and the lack of an accurate serological marker is a challenge to the development of new rotavirus vaccines. Serological responses to rotavirus NSP2 occur following wild-type infection; however, it is unknown if serological responses to NSP2 occur following administration of rotavirus vaccines. The phase IIa immunogenicity...
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