Article
Rotavirus nonstructural protein NSP4 induces heterotypic antibody responses during natural infection in children.
The Journal of infectious diseases - 1 Jun 2003
Ray Pratima, Malik Jyoti, Singh Ravi K, Bhatnagar Shinjini, Bahl Rajiv, Kumar Ramesh, Bhan Maharaj K
Abstract excerpt
Seroconversion of immunoglobulin A (IgA) and immunoglobulin G (IgG) (> or =4-fold rise) to rotavirus nonstructural protein 4 (NSP4) was determined, by use of enzyme-linked immunosorbent assay with fusion proteins glutathione S-transferase (GST)-NSP4 from strains SA11 (A), 116E (B), and RRV (C), in 40 children with acute rotavirus gastroenteritis and in 30 with the same disease due to other pathogens. The IgG...
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